When is the best time to make jokes?

When you are ill, because they are sick

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Why are astrophysicists always nervous before they launch a new satellite?

It can be a very Hubble-ing experience. These jokes may not be funny for you, but they are Fermi.

Why aren't there any knock knock jokes about America?

Because Freedom Rings.

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When's the best time of day to start a diet?

4:00 For:Klock

Why do mycologists have such a good time?

Because they hang around the fungi.